10 Best Antihistamines in the Philippines 2025 | Buying Guide Reviewed by Doctor
Looking for the best antihistamine to relieve sneezing, itchy skin, or runny nose? With so many options available over the counter, it can be hard to know which one works best for your symptoms.
In this guide, we asked Dr. Eron Tan, a board-certified physician, to share expert advice on how to choose. We also rounded up widely available options you can buy on Lazada and Shopee.
Quick List - Top Antihistamine
Watsons
Quick Relief You Can Count On, Anytime Allergies Strike
Dr. Tan is a Family and Occupational Medicine doctor and college faculty member with expertise in clinical care, preventive medicine, and evidence-based practice. With a strong background in primary and secondary care, research, and community-oriented primary care, he simplifies complex health topics for readers. His experience in occupational health provides insights into workplace well-being and safety, ensuring health-related decisions are grounded in research and reliable medical knowledge.
Our recommendation articles are carefully researched and crafted by the mybest Philippines team of writers and editors. To stay true to our company’s mission and vision to help users’ selection process easier, we also collaborate with experts from various fields to ensure that our content stays factual and useful.
The expert oversees the Buying Guide only, and does not determine the products and services featured.
Table of Contents
- Why You Can Trust Us
- Understand Potential Side Effects of Antihistamine and When to Use With Caution
- How to Choose an Antihistamine – Buying Guide
- Choose the Right Type and Format Based on Your Symptoms1
- Choose Between Drowsy and Non-Drowsy Antihistamines Based on Your Daily Activities2
- Follow Proper Dosage and Timing for Adults3
- For Pregnant or Breastfeeding Women, Look for OB-Recommended Options4
- For Kids, Go for Age-Appropriate Formulations in Syrup or Drops5
- Frequently Asked Questions
- How Much Antihistamine Can I Take in 24 Hours?
- Can I Take Sinupret With Antihistamine?
- What Can You Not Take With Antihistamines?
- More Ways to Support Allergy Relief and Boost Wellness
- How We Chose and Ranked Our Product Recommendations
Why You Can Trust Us
Every mybest article is crafted with hours of in-depth research and interviews with experts. Each month, we are continually expanding our database of products based on our research. By emphasizing user insight and reliable information, we deliver trustworthy content to readers.
Understand Potential Side Effects of Antihistamine and When to Use With Caution
Common side effects include drowsiness, dry mouth, dizziness, and gastrointestinal issues. First-generation types may also cause cognitive impairment, especially in the elderly.
While antihistamines are generally safe, first-generation options like diphenhydramine can cause side effects, particularly when used without medical guidance. These may include drowsiness, dry mouth, headaches, dizziness, and gastrointestinal discomfort. Children under 2, the elderly, and those with liver or kidney problems are also more prone to side effects.
There are three generations of antihistamines, each with different levels of sedation and side effects:
First-generation: Older types like diphenhydramine that can make you very sleepy and affect alertness.
Second-generation: Common options like cetirizine or loratadine that are less likely to cause drowsiness.
Third-generation: Newer types like desloratadine or levocetirizine that are gentler on the body with fewer side effects.
How to Choose an Antihistamine – Buying Guide
Whether you're looking for a non-drowsy option for daytime use or something fast-acting for itchy skin and hives, choosing the right antihistamine depends on your symptoms, age, and health condition. Below, we break down the key features to look for based on expert advice from Dr. Eron Tan.
Choose the Right Type and Format Based on Your Symptoms
Antihistamines come in different forms, each suited for specific allergy symptoms. Knowing which one to choose can help you get faster and more targeted relief. Below are the most common formats and when to use them.
For Skin Allergies Like Hives or Bug Bites: Try Creams or Fast-Acting Oral Antihistamines
Cetirizine and levocetirizine are used for urticaria or hives--not to be confused with eczema. Creams are also helpful for localized skin reactions.
When your allergies show up as itchy, raised rashes or if you have intense bug bites, a topical antihistamine cream can bring relief directly where it’s needed. These are ideal for small, irritated patches on the skin.
But if the itching is more intense or spreads across your body, fast-acting oral antihistamines like cetirizine or levocetirizine are more effective. However, if you have eczema, keep in mind that antihistamines are not the main treatment. Eczema usually requires other remedies, like moisturizers or steroids, to address inflammation.
For Sneezing, Itchy Throat, or Runny Nose: Go for Oral Tablets or Nasal Sprays
Use nasal corticosteroid sprays (e.g., mometasone, fluticasone) for persistent allergic rhinitis. Use oral antihistamines for episodic, mild symptoms like itching and sneezing.
If your allergy symptoms include sneezing, itchy throat, or runny nose, oral antihistamines like loratadine in tablet or syrup form are a good place to start. They're convenient for daily use and relieve most upper respiratory symptoms.
However, if you're also experiencing nasal congestion or post-nasal drip that won't go away, nasal sprays—particularly corticosteroid-based ones like mometasone—can help clear your airways more effectively. For moderate to severe cases, it's best to consult a doctor for advice on what medicine will work best for you.
For General or Widespread Allergies: Opt for Oral Antihistamines That Act Systemically
Tablets and syrups are best for systemic symptoms. They’re helpful when multiple areas—like the eyes, skin, and nose—are affected.
If you're experiencing several allergy symptoms at the same time, such as sneezing, watery eyes, and itchy skin, oral antihistamines are your best option for overall relief. These medicines work throughout the body by targeting histamine in the bloodstream, making them effective even when the trigger isn’t clear.
Commonly recommended active ingredients include cetirizine, levocetirizine, loratadine, and desloratadine. These second- and third-generation types are preferred for daily or long-term use since they have fewer side effects and are less likely to cause drowsiness.
Choose Between Drowsy and Non-Drowsy Antihistamines Based on Your Daily Activities
First-generation antihistamines, like diphenhydramine, cause drowsiness and are best taken at night. Second- and third-generation types, such as cetirizine and desloratadine, are less sedating and suitable for work or school.
Some antihistamines can make you sleepy, while others are suitable for daytime use. If you need allergy relief but still want to stay alert at work or school, go for non-drowsy or less sedating options like cetirizine, loratadine, or desloratadine. These are second- and third-generation antihistamines, designed to minimize brain-related side effects.
On the other hand, if your symptoms bother you at night or you have trouble sleeping due to allergies, a drowsy type like diphenhydramine may help with both itching and sleep.
Follow Proper Dosage and Timing for Adults
Stick to the right dose and timing to avoid side effects, especially with sedating types like diphenhydramine.
Taking the right dose helps you get symptom relief without unwanted side effects like drowsiness or dizziness. Below are the common dosages for adults:
Cetirizine: 10 mg once daily (for urticaria, it may be taken twice daily if needed)
Loratadine: 10 mg once daily
Diphenhydramine: 25–50 mg every 4 to 6 hours, only under medical supervision due to sedative and anticholinergic effects
Take 1–2 hours before exposure for seasonal or episodic allergies. Daily use for chronic symptoms.
For Pregnant or Breastfeeding Women, Look for OB-Recommended Options
Loratadine and cetirizine are often recommended during pregnancy and breastfeeding, but it's best to avoid any antihistamines in the first trimester.
If you're pregnant or breastfeeding, choosing an antihistamine requires extra caution. While some second-generation options are considered safer, it’s best to avoid any antihistamine during the first trimester unless prescribed by your OB-GYN. Loratadine and cetirizine are commonly recommended because they pose minimal risk and transfer only small amounts through breast milk.
For those with mild symptoms, non-drug alternatives like nasal saline sprays or avoiding known allergens can be effective. No matter your choice, don’t self-medicate—always consult your OB-GYN or pediatrician to make sure your allergy treatment is safe for both you and your baby.
For Kids, Go for Age-Appropriate Formulations in Syrup or Drops
Children require special care when it comes to allergy medication. Antihistamines for kids should match their age, weight, and symptom type.
For Toddlers and Younger Children: Syrups With Clear Age Labels
For children under 6, use weight- and age-appropriate doses. Avoid sedating agents and use liquid second-gen like cetirizine (≥6 months).
For babies and toddlers, choose antihistamine syrups that clearly indicate the minimum age for use. Cetirizine is often recommended starting at 6 months old, while loratadine may be used for children age 2 and up. Dosages should be based on your child’s weight, and always confirmed by a doctor or stated on the packaging. For example:
Cetirizine: 2.5 mg once daily for children aged 6 months to 2 years
Loratadine: 5 mg once daily for children aged 2 to 5 years
Avoid sedating antihistamines like diphenhydramine in children under 2, as these may cause agitation, seizures, or respiratory issues.
Always use a proper dosing device, like an oral syringe, to avoid mistakes.
For School-Age Kids: Non-Drowsy Options With Palatable Flavors
Use non-sedating antihistamines to avoid drowsiness and help kids stay alert during the day.
Older children who need allergy relief during school hours benefit most from non-drowsy antihistamines that won’t interfere with learning, attention, or behavior. These often come in child-friendly flavors and are available in both syrup and chewable tablet forms.
If your child has sensitivities to artificial colors or sweeteners, choose versions that are dye-free or sugar-free to minimize the risk of additional reactions.
10 Best Antihistamines to Buy Online
Products | Image | Click to purchase | Key features | Details | |||||
|---|---|---|---|---|---|---|---|---|---|
Type | Format | Dose | Safe for Pregnant Women | Safe for Kids | |||||
1 | Unilab Allerta | | Relieves Nasal Congestion From Allergies in Just 15 Minutes | Non-drowsy | Tablet | 10mg Loratadine | |||
2 | Bayer Claritin | | Breathe Easy With All-Day Relief From Over 200 Different Allergens | Non-drowsy | Tablet | 10mg Loratadine | |||
3 | Benadryl AH Antihistamine 25mg 4s | | Fast-Acting Allergy Relief That Helps You Rest Easy | Drowsy | Capsule | 25mg Diphenhydramine HCl | |||
4 | Watsons Generics Cetirizine 10mg 8+2 Capsules | | Quick Relief You Can Count On, Anytime Allergies Strike | Non-drowsy | Capsule | 10mg Cetirizine HCl | |||
5 | RiteMED Cetirizine 20 Tablets (Allergy Relief) | | A Fast and Affordable Relief for Allergy Symptoms | Non-drowsy | Tablet | 10mg Cetirizine Dihydrochloride | |||
6 | Benadryl Allergy Medicine, Antihistamine Syrup 60ml | | Provides Effective Relief for Everyday Allergies | Drowsy | Syrup | 12.5mg Diphenhydramine HCl/5mL | |||
7 | Unilab Allerkid Cetirizine Syrup 5mg 60ml | | Fast, Kid-Friendly Relief from Allergy Symptoms | Non-drowsy | Syrup | 5mg Cetirizine HCl/5mL | |||
8 | Benadryl Extra Strength Itch Stopping Cream | | Addresses Allergy Symptoms and Skin Inflammation | Topical Cream | 2% Diphenhydramine HCl/28.3g | ||||
9 | Bayer ClariClear | | Fast-Acting Nasal Spray for Up to 12 Hours of Congestion Relief | Non-drowsy | Nasal Spray | 0.05% Oxymetazoline HCl/500mL | |||
10 | Unilab Loraped Syrup 60ml (Loratadine + Phenylephrine Hcl) | | Soothes Allergies and Clears Your Nose to Make You Feel Better Fast | Non-drowsy | Syrup | 60ml Loratadine + Phenylephrine Hcl | |||
Relieves Nasal Congestion From Allergies in Just 15 Minutes
- Delivers fast-acting, non-drowsy relief from allergies
- Contains 10mg of loratadine, an anti-allergy ingredient that blocks histamine to alleviate symptoms
- Loratadine helps prevent drowsiness and dizziness, unlike other allergy medicines
- Starts working in as little as 15 minutes for quick relief
- Eases common allergy symptoms like sneezing, runny nose, and itchy eyes
Reviews mention:
Customers love how it doesn't cause drowsiness while still providing effective allergy relief. The fast-acting formula stands out, with many noticing results within minutes. It's also praised for being reliable in easing allergy symptoms without the side effects of other medications.| Type | Non-drowsy |
|---|---|
| Format | Tablet |
| Dose | 10mg Loratadine |
| Safe for Pregnant Women | |
| Safe for Kids |
Breathe Easy With All-Day Relief From Over 200 Different Allergens
- Each 10mg tablet contains loratadine, a powerful antihistamine for allergy relief
- Works quickly, starting to ease symptoms in as little as 15 minutes
- Targets multiple symptoms, including sneezing, runny nose, itchy or watery eyes, and itchy nose or throat
- Offers 24-hour, non-drowsy allergy relief, so you can enjoy your day without feeling sleepy
- Effective against over 200 different allergens like pet dander, dust, mold, pollen, grass, and tree pollen
Reviews mention:
Customers love the convenient packaging, especially the added bonus of extra tablets. The non-drowsy formula is perfect for all-day use, allowing users to stay active without feeling tired. It’s also frequently recommended for its effectiveness in relieving a range of allergy symptoms.| Type | Non-drowsy |
|---|---|
| Format | Tablet |
| Dose | 10mg Loratadine |
| Safe for Pregnant Women | |
| Safe for Kids |
Fast-Acting Allergy Relief That Helps You Rest Easy
Features and benefits:
- Soothes itchy skin and hives
- Ideal for nighttime use
- Average Benadryl dose lasts 4 to 6 hours
Reviews mention:
Many users say this product provides fast relief from allergy symptoms like sneezing, runny nose, itchy eyes, and skin rashes. It's a favorite for those who want restful sleep while dealing with allergies, thanks to its drowsy effect. People also like keeping it on hand because it's reliable and works whenever allergy attacks come unexpectedly.
| Type | Drowsy |
|---|---|
| Format | Capsule |
| Dose | 25mg Diphenhydramine HCl |
| Safe for Pregnant Women | |
| Safe for Kids |
Quick Relief You Can Count On, Anytime Allergies Strike
Features and benefits:
- Suitable for kids and pregnant women
- Convenient capsule form
- 8+2 capsule pack offers extra value
Reviews mention:
Users love how this product offers fast, effective relief from both nasal and skin allergies. Many keep it in their bags or medicine kits because it’s convenient, easy to swallow, and affordable. It’s also praised for being reliable and doctor-recommended, making it a trusted choice for allergy-prone individuals.
| Type | Non-drowsy |
|---|---|
| Format | Capsule |
| Dose | 10mg Cetirizine HCl |
| Safe for Pregnant Women | |
| Safe for Kids |
A Fast and Affordable Relief for Allergy Symptoms
Features and benefits:
- Effective for allergic conjunctivitis or eye allergy
- Once-daily dosing for adults and children 12 years and up
- Low risk of drowsiness at the recommended dose
Reviews mention:
Users say this product gives fast and reliable relief from allergic rhinitis and skin allergies, including itch and rash from hives (urticaria). Many appreciate that it’s affordable yet effective, making it a go-to option for daily use. It’s also praised for being easy to take and suitable for both adults and kids, earning the trust of families who deal with frequent allergy symptoms.
| Type | Non-drowsy |
|---|---|
| Format | Tablet |
| Dose | 10mg Cetirizine Dihydrochloride |
| Safe for Pregnant Women | |
| Safe for Kids |
Provides Effective Relief for Everyday Allergies
Features and benefits:
- Helps users rest better with its calming, drowsy formula
- Comes in a syrup form that’s also easy for children to take
- Trusted for generations as a reliable solution for allergy relief
Reviews mention:
Filipinos trust Benadryl because it provides fast and effective relief from common allergy symptoms like pagbabahing and itchy eyes. Many love it for its cooling, pleasant taste. It is a well-recommended, go-to brand, perfect for people with hay fever, skin rashes, or everyday allergies.
| Type | Drowsy |
|---|---|
| Format | Syrup |
| Dose | 12.5mg Diphenhydramine HCl/5mL |
| Safe for Pregnant Women | |
| Safe for Kids |
Fast, Kid-Friendly Relief from Allergy Symptoms
Features and benefits:
- Eases sneezing, runny nose, and itchy eyes
- Can be taken with an empty stomach
- Works in as fast as 20 minutes
Reviews mention:
Parents love that Allerkid provides quick and effective relief from both nasal and skin allergies. It’s a trusted brand recommended by doctors, and many say it’s their go-to for their children’s allergy needs. The syrup is also easy to give and kid-approved in taste, making it less of a struggle to administer to kids during allergy season.
| Type | Non-drowsy |
|---|---|
| Format | Syrup |
| Dose | 5mg Cetirizine HCl/5mL |
| Safe for Pregnant Women | |
| Safe for Kids |
Addresses Allergy Symptoms and Skin Inflammation
Features and benefits:
- Provides quick relief from pain and itching due to insect bites, burns, sunburn, and allergens from kasoy and mango trees
- Helps to dry up the oozing and weeping associated with rashes
- Ideal for outdoor activities
Reviews mention:
Users say this cream gives fast, effective relief for everything from mosquito bites to mild burns and rashes. Many love that it’s easy to use, dries quickly, and feels cool on the skin, making it great for traveling, hiking, camping, or playing outdoors. It’s also described as better than regular cortisone by some. Suitable for adults and children aged 2 and older.
| Type | |
|---|---|
| Format | Topical Cream |
| Dose | 2% Diphenhydramine HCl/28.3g |
| Safe for Pregnant Women | |
| Safe for Kids |
Fast-Acting Nasal Spray for Up to 12 Hours of Congestion Relief
- Quickly relieves a blocked nose caused by colds, sinusitis, hay fever, or other allergies
- Uses 0.05% oxymetazoline hydrochloride to shrink swollen blood vessels and clear nasal passages
- Starts working in under a minute to ease congestion fast
- Offers up to 12 hours of lasting relief, so you can breathe easier throughout the day or night
- Comes in a handy nasal spray format for easy and direct application
Reviews mention:
Many users mention how quickly it opens up their nasal passages, especially during allergy flare-ups. It’s also noted for being easy to use and handy to keep around. Several say they felt relief from clogged nostrils almost immediately after spraying.| Type | Non-drowsy |
|---|---|
| Format | Nasal Spray |
| Dose | 0.05% Oxymetazoline HCl/500mL |
| Safe for Pregnant Women | |
| Safe for Kids |
UnilabLoraped Syrup 60ml (Loratadine + Phenylephrine Hcl)
Soothes Allergies and Clears Your Nose to Make You Feel Better Fast
Features and benefits:
• Easy to administer, especially to kids
• Less drowsy formula lets you stay alert while healing
• Combines antihistamine and decongestant for complete allergy relief
Reviews mention:
Users say Loraped provides fast and noticeable relief from nasal congestion, pagbabahing, and even postnasal drip. Many shared that it helped clear their sinuses and stop persistent coughing, especially during allergy season and tag-ulan. It’s also praised for being banayad on the stomach and non-drowsy, making it ideal for children and adults with recurring allergy symptoms.
| Type | Non-drowsy |
|---|---|
| Format | Syrup |
| Dose | 60ml Loratadine + Phenylephrine Hcl |
| Safe for Pregnant Women | |
| Safe for Kids |
How Much Antihistamine Can I Take in 24 Hours?
The recommended dosage depends on the specific antihistamine. Most second-generation types, like cetirizine or loratadine, are taken once a day at 10 mg. In some cases, your doctor may allow you to take them twice daily.
First-generation antihistamines like diphenhydramine can be taken up to 25–50 mg every 4–6 hours, but always follow the label or your doctor’s advice. Overdosing may cause drowsiness, confusion, or serious side effects.
Can I Take Sinupret With Antihistamine?
Yes, in most cases, Sinupret (a herbal supplement used for sinus symptoms) can be safely taken alongside antihistamines. There are no major known interactions between Sinupret and common antihistamines like cetirizine or loratadine. However, it’s still best to consult your doctor, especially if you are taking other medications or managing chronic conditions.
What Can You Not Take With Antihistamines?
Avoid combining antihistamines—especially first-generation ones—with alcohol or other sedatives, as this can increase the risk of extreme drowsiness, slowed breathing, and impaired coordination. Also, be cautious when taking other allergy medications, cold remedies, or sleeping pills that may contain similar ingredients. Always read labels and consult a healthcare provider to avoid accidental overdose or drug interactions.
More Ways to Support Allergy Relief and Boost Wellness
Explore these expert-reviewed guides for added support in your allergy care routine.
How We Chose and Ranked Our Product Recommendations
Our buying guide was carefully researched and crafted by the mybest team of writers and editors, in collaboration with the expert featured in this article. We used the buying guide as a basis for choosing and ranking the product recommendations, and we looked at reviews and ratings from different E-commerce sites like Lazada, Shopee, and more.
Top 5 Antihistamine
No. 1: Unilab｜Allerta
No. 2: Bayer｜Claritin
No. 3: Benadryl｜AH Antihistamine 25mg 4s
No. 4: Watsons｜Generics Cetirizine 10mg 8+2 Capsules
No. 5: RiteMED｜Cetirizine 20 Tablets (Allergy Relief)
View Full RankingThe descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.
Most ViewedFeatured Rankings Similar to Allergy relief medicines
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