10 Best Medicines for Toothache in the Philippines 2026 | Buying Guide Reviewed by Dentist
A toothache can be both painful and disruptive, making even simple tasks difficult. Fortunately, the right treatment can provide quick relief by easing inflammation and sensitivity. Whether you need an over-the-counter pain reliever or a topical gel, choosing the best medicine for toothache can make a significant difference in managing discomfort effectively.
These pain relief options are readily available in pharmacies and online stores like Lazada and Shopee. To help you find the most effective solution, check out our buying guide fact-checked by dentist Dr. Rona Navarro, and our top recommendations below.
Quick List - Top Medicines for Toothache

Dr. Rona Navarro is an alumna of The University of Perpetual Help Laguna, College of Dentistry Batch 2005. She specializes in Orthodontics with board certification and is licensed by the Philippine Regulatory Commission, a member of the Philippine Dental Association, and the International Association of Orthodontics. She has been a private dental practitioner for 20 years, dedicated to delivering proficient and comprehensive oral health care within her community. Compassionate and skilled, she has consistently maintained high patient retention rates over the past two decades, demonstrating patient satisfaction in restorative, prosthodontic, and orthodontic treatments.

Our recommendation articles are carefully researched and crafted by the mybest Philippines team of writers and editors. To stay true to our company’s mission and vision to help users’ selection process easier, we also collaborate with experts from various fields to ensure that our content stays factual and useful.
The expert oversees the Buying Guide only, and does not determine the products and services featured.
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Understanding Toothache and Safe Pain Relief Options
What Causes Toothache?

- Tooth decay – The leading cause of tooth pain due to bacterial damage.
Dental abscesses or infections – Pus buildup from untreated infections causes severe pain and swelling.
Cracked or damaged teeth – Fractures can expose nerves, leading to discomfort.
Loose or broken fillings – A damaged filling can expose the sensitive inner tooth.
Impacted teeth – Particularly wisdom teeth that partially erupt without enough space.
Braces issues – Discomfort caused by orthodontic adjustments.
Gum disease – Inflammation and infection affecting the gums and tooth stability.
Teeth grinding (bruxism) – Excessive grinding that wears down enamel and causes pain.
Tooth sensitivity – Pain triggered by hot, cold, or sweet foods.

Prevention is better than cure. Routine dental examination every 6 months is recommended.
Consult a Doctor Before Taking Pain Relievers During Pregnancy and Breastfeeding

Pregnant and breastfeeding women should be cautious when taking pain relievers. Paracetamol is the safest option for pain relief, while Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and mefenamic acid should be avoided, especially after 20 weeks of pregnancy, due to potential risks to the baby.
Since medicine labels may not always indicate pregnancy safety, it’s best to consult a doctor before taking any medication to ensure both maternal and infant health.

20 weeks onwards, it may cause rare and serious kidney problems in the unborn baby. Fetal renal dysfunction and neonatal complications are most likely to occur.
Warning: Pain Relievers Are Temporary Solutions, Not a Cure

How to Choose a Medicine for Toothache - Buying Guide
Down with a bad toothache? Finding the right over-the-counter medicine can be a lifesaver, but with so many choices, it's hard to know what actually works. Before you grab just anything, here's a quick guide to help you choose the best medicine for your toothache.
Select the Right Pain Reliever Based on the Severity of Pain
Toothaches can range from mild discomfort to severe, persistent pain. Choosing the right medicine depends on the severity of symptoms and the cause of the pain. For minor toothaches, over-the-counter (OTC) pain relievers can help, while more severe cases may require stronger medications or professional intervention.
Mild to Moderate Pain: Common OTC Pain Relievers Like Paracetamol

Paracetamol – A safe and effective choice for pain relief; however, daily intake should not exceed 4000mg to prevent liver damage.
Ibuprofen – Reduces both pain and inflammation; best taken with food to avoid stomach irritation, especially in high doses.
Mefenamic Acid – Another NSAID that helps relieve pain and swelling; should be taken with meals to minimize stomach discomfort.
These medications are easily accessible in tablet or capsule form and can provide quick relief for minor toothaches. Always follow the recommended dosage to ensure safe and effective use.
Severe or Persistent Tooth Pain and Swelling: Stronger NSAIDs Like Ibuprofen 400mg

For intense or prolonged tooth pain, higher-dose NSAIDs can provide stronger relief. These are particularly effective for severe pain caused by deep cavities, impacted wisdom teeth, or gum swelling.
Ibuprofen (400mg) – Helps manage severe pain and inflammation. The standard dosage for OTC ibuprofen is 200mg every 4–6 hours, with a maximum daily dose of 1200mg. Prescription-strength doses of 600mg or 800mg are available but should only be taken under medical supervision due to potential side effects.
Mefenamic Acid (500mg) – Provides strong pain relief and reduces swelling; should be taken with food to minimize stomach irritation.
While these medications can help control pain, they are not a permanent solution. If pain persists despite medication or is accompanied by fever, swelling, or pus, it may indicate an infection requiring antibiotics or professional treatment. Consulting a dentist is crucial to prevent further complications.

Higher doses are generally effective, but depending on the person's age, an overdose may occur. The proper dosage requires a dentist's prescription. For pregnant women or those who are expecting, it's best to consult an OBGYN before taking any pain reliever.
Consider Topical Pain Relievers Like Benzocaine Gel for Fast, Localized Relief

For those who prefer non-oral options, topical pain relievers like benzocaine gels and oral pain relief sprays can provide temporary relief by numbing the affected area. These products work directly on the gums or tooth, making them ideal for targeting specific pain points, such as cavities or erupting wisdom teeth.
However, their effects wear off quickly, so they are best used alongside oral pain relievers for sustained relief. Overuse of numbing gels can cause irritation, so following the recommended application is important. If the pain is severe or persistent, a dentist should still be consulted for proper diagnosis and treatment.
Prioritize Safety: Choose FDA-Approved Medications and Trusted Sellers

Always check if a medication is FDA-approved to ensure it has been tested for safety and effectiveness. You can verify its registration on the Philippine FDA website to avoid unregistered medicines, which may contain harmful or ineffective ingredients.
To ensure authenticity, buy only from licensed pharmacies, official brand stores, or reputable sellers on platforms like Lazada, Shopee, Watsons, and Mercury Drug. Check packaging, expiration dates, and proper labels to avoid counterfeit products. When in doubt, consult a pharmacist or purchase from a physical pharmacy for a safer and more reliable option.
10 Best Medicines for Toothache to Buy Online
Products | Image | Click to purchase | Key features | Details | |||||
|---|---|---|---|---|---|---|---|---|---|
Key Ingredients | Best For | FDA-Approved | Content | Dosage | |||||
1 | Unilab Biogesic | ![]() | Fast-Acting Paracetamol Tablets for Common Aches | Paracetamol | Mild to Moderate Pain | 10 Tablets | 500 mg | ||
2 | Bayer Saridon | ![]() | Triple-Action Tablets for Fever and Pain Relief in Just 5 Minutes | Paracetamol, Propyphenazone, Caffeine | Mild to Moderate Pain | 10 Tablets | 250 mg / 150 mg / 50 mg | ||
3 | Unilab Rexidol Forte | ![]() | Get Fast Relief With a Paracetamol and Caffeine Combo | Paracetamol | Mild to Moderate Pain | 100 Tablets | 500 mg / 65 mg | ||
4 | TGP Toothache Drops Oral | ![]() | Clove Oil-Infused Toothache Drops With a Soothing Effect | Eugenol | Mild to Moderate Pain | 7.5 mL | 1.25mg | ||
5 | Unilab Medicol Advance | ![]() | Starts Working in 5 Minutes To Relieve Pain | Ibuprofen | Severe or Persistent Tooth Pain | 10 Softgels | 400mg | ||
6 | Dann's Toothache Drops | ![]() | Fast-Acting Relief for Sudden Dental Pain | Eugenol | Mild to Moderate Pain | 7.5mL | 1.25mg | ||
7 | Advil Liquigel | ![]() | Reliable Pain Relief for Headaches, Fever, and Body Aches | Ibuprofen | Severe or Persistent Tooth Pain | 10 Softgels | 400mg | ||
8 | J. Chemie Eugenol Toothache Drops | ![]() | Soothes Toothache Pain Rapidly With Eugenol | Eugenol | Severe or Persistent Tooth Pain | 7.5mL | 1.25mg | ||
9 | Southstar Drug Mefenamic Acid | ![]() | Budget-Friendly Pain Relief for Everyday Aches | Mefenamic Acid | Mild to Moderate Pain | 1 Tablet | 500 mg | ||
10 | Unilab Dolfenal | ![]() | Targets Pain at Its Source With Mefenamic Acid | Mefenamic Acid | Severe or Persistent Tooth Pain | 1 Tablet | 250 mg | ||
Fast-Acting Paracetamol Tablets for Common Aches
Features and benefits:
- Relieves fever in 6 minutes and headaches in 25 minutes with 500mg of paracetamol
- Treats common body pains and toothache with an easy-to-take tablet
- Provides gentle relief that can be taken on an empty stomach
- Contains pure paracetamol, safe for pregnant women, breastfeeding moms, and the elderly
Reviews mention:
Users appreciate its reliable relief for headaches and fever, though some still find the tablet slightly large. Pregnant and breastfeeding women also like having a safe, effective option. Overall, many rely on it as their go-to for quick recovery from fever and common aches.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Tablets |
BayerSaridon
| Key Ingredients | Paracetamol, Propyphenazone, Caffeine |
|---|---|
| Dosage | 250 mg / 150 mg / 50 mg |
Triple-Action Tablets for Fever and Pain Relief in Just 5 Minutes
Features and benefits:
- Combines paracetamol, propyphenazone, caffeine for fast pain relief
- Relieves headaches, fever, body pain, dysmenorrhea, and toothache with a triple-action formula
- Provides easy-to-take tablets for relief whenever needed
- Ensures faster absorption and symptom relief in fast-dissolving tablets
Reviews mention:
Buyers who suffer from migraines frequently mention the swift and lasting relief this triple-action formula provides. It is a preferred choice for severe headaches, with many opting for it over other brands. Its reliable effectiveness keeps them coming back.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Tablets |
UnilabRexidol Forte
| Key Ingredients | Paracetamol |
|---|---|
| Dosage | 500 mg / 65 mg |
Get Fast Relief With a Paracetamol and Caffeine Combo
Features and benefits:
- Combines paracetamol with caffeine to enhance and prolong its effect
- Relieves headaches, body aches, fever, and tiredness with its dual-action formula
- Provides relief in as fast as 30 minutes
- Available as a fast-acting over-the-counter pain reliever
Reviews mention:
Users find this combination effective for tension headaches and migraines and note that it also helps improve alertness. A few mention that clearer caffeine warnings would benefit caffeine-sensitive individuals. Overall, buyers like its fast and reliable relief.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 100 Tablets |
TGPToothache Drops Oral
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
Clove Oil-Infused Toothache Drops With a Soothing Effect
Features and benefits:
- Infused with eugenol, a natural compound derived from clove oil,
- Delivers pain-relieving, anti-inflammatory, and antibacterial effects to help soothe discomfort and prevent infections
- Blended with zinc oxide, it can also serve as an anodyne dental filling, providing lasting relief from aching teeth
- The fast-acting formula offers immediate, targeted relief for tooth pain
- Accessible and easy to apply for practical, on-the-spot dental care
Reviews mention:
Many users appreciate its fast-acting effect, though some note the slightly spicy taste caused by clove oil. The powerful numbing sensation makes it a must-have for sudden or persistent tooth pain, with buyers finding it practical and reliable for immediate relief.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5 mL |
UnilabMedicol Advance
| Key Ingredients | Ibuprofen |
|---|---|
| Dosage | 400mg |
Starts Working in 5 Minutes To Relieve Pain
Features and benefits:
- Contains 200mg of ibuprofen to relieve mild to moderate pain
- Acts as an NSAID for reducing inflammation in joints and muscles
- Relieves pain from headaches, menstrual cramps, dental pain, and post-operative discomfort
- Comes in easy-to-take tablets for fast, convenient relief
Reviews mention:
Customers share that this tablet works quickly for headaches, stomach discomfort, and migraines. Many also note that it’s effective for period pain and reliable to keep on hand for sudden flare-ups. Users appreciate how easily it can be taken, making it a go-to option when pain hits.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Softgels |
Dann'sToothache Drops
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
Fast-Acting Relief for Sudden Dental Pain
- Provides quick numbing of toothache pain using clove oil, a natural anesthetic trusted for rapid relief
- Relieves gum irritation and oral discomfort with the anti-inflammatory effects of capsicum and camphor
- Targets nerve sensitivity for more direct, localized comfort at the source of pain
- Convenient dropper format for easy application right where it hurts
Reviews mention:
Many users highlight the fast relief these drops offer for sudden dental pain, appreciating how simple they are to apply right at the sore spot. Some note that the numbing effect is noticeable and provides comfort between dentist visits. However, people also mention it's a temporary solution and should not replace professional dental care.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5mL |
Reliable Pain Relief for Headaches, Fever, and Body Aches
- Contains 200 mg of ibuprofen, which reduces fever, inflammation, and pain
- Works almost three times faster than standard ibuprofen tablets for quick relief
- Provides stronger pain control than paracetamol for tough headaches and body aches
- Comes in an easy-to-swallow softgel with no bitter aftertaste
Reviews mention:
Customers frequently mention how quickly this softgel relieves headaches and muscle pain that paracetamol doesn’t fully address. The softgel capsule glides down easily, a feature many appreciate, especially when taking medicine feels harder during sickness.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Softgels |
J. ChemieEugenol Toothache Drops
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
Soothes Toothache Pain Rapidly With Eugenol
- Relieves toothache quickly with localized eugenol action
- Helps reduce inflammation and minor oral infections naturally
- Easy cotton-swab application for targeted, temporary relief
- 7.5 ml bottle allows controlled dosing with minimal waste
Reviews mention:
Buyers report fast numbing for severe toothaches, often using it overnight until dentist appointments. Many highlight its clove-like scent as familiar and comforting from traditional remedies. Users caution about brief stinging on open wounds and stress seeing a dentist promptly.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5mL |
Southstar DrugMefenamic Acid
| Key Ingredients | Mefenamic Acid |
|---|---|
| Dosage | 500 mg |
Budget-Friendly Pain Relief for Everyday Aches
Features and benefits:
- Targets moderate pain, including headache and menstrual pain like dysmenorrhea
- Acts as an NSAID (Non-Steroidal Anti-Inflammatory Drug) to reduce inflammation and fever
- Provides a widely trusted and accessible pain relief option
Reviews mention:
A lot of users consider this a trusted medication because it's so reliable when they need fast relief. People say it's especially great for tackling stubborn headaches and getting rid of menstrual cramps quickly. Plus, reviewers appreciate that the tablets are easy to swallow and that the delivery options make getting them very convenient.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 1 Tablet |
UnilabDolfenal
| Key Ingredients | Mefenamic Acid |
|---|---|
| Dosage | 250 mg |
Targets Pain at Its Source With Mefenamic Acid
Features and benefits:
- Handles severe pain from cramps, dental, or joint aches with 250mg of mefenamic acid
- Treats pain and inflammation simultaneously as an NSAID
- Relieves menstrual cramps and discomfort effectively with a film-coated tablet
- Comes from a trusted Filipino pharmaceutical company for reliable pain relief
Reviews mention:
Reviewers often turn to this tablet for severe aches, including intense headaches and dental pain. Many trust its effectiveness and the reliability of a trusted company like Unilab. They frequently choose it when they need strong, dependable relief.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 1 Tablet |
Frequently Asked Questions
Below are some of the most asked questions on the web answered by the mybest team.
Do Pain Relievers Cure Toothache?
Is Combining Pain Relievers Safe?
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How We Chose and Ranked Our Product Recommendations
Our buying guide was carefully researched and crafted by the mybest team of writers and editors, in collaboration with the expert featured in this article. We used the buying guide as a basis for choosing and ranking the product recommendations, and we looked at reviews and ratings from different E-commerce sites like Lazada, Shopee, and more.
Top 5 Medicines for Toothache
No. 1: Unilab|Biogesic
No. 2: Bayer|Saridon
No. 3: Unilab|Rexidol Forte
No. 4: TGP|Toothache Drops Oral
No. 5: Unilab|Medicol Advance
View Full RankingThe descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.