




A toothache can be both painful and disruptive, making even simple tasks difficult. Fortunately, the right treatment can provide quick relief by easing inflammation and sensitivity. Whether you need an over-the-counter pain reliever or a topical gel, choosing the best medicine for toothache can make a significant difference in managing discomfort effectively.
These pain relief options are readily available in pharmacies and online stores like Lazada and Shopee. To help you find the most effective solution, check out our buying guide fact-checked by dentist Dr. Rona Navarro, and our top recommendations below.
Quick List - Top Medicines for Toothache

Dr. Rona Navarro is an alumna of The University of Perpetual Help Laguna, College of Dentistry Batch 2005. She specializes in Orthodontics with board certification and is licensed by the Philippine Regulatory Commission, a member of the Philippine Dental Association, and the International Association of Orthodontics. She has been a private dental practitioner for 20 years, dedicated to delivering proficient and comprehensive oral health care within her community. Compassionate and skilled, she has consistently maintained high patient retention rates over the past two decades, demonstrating patient satisfaction in restorative, prosthodontic, and orthodontic treatments.

Our recommendation articles are carefully researched and crafted by the mybest Philippines team of writers and editors. To stay true to our company’s mission and vision to help users’ selection process easier, we also collaborate with experts from various fields to ensure that our content stays factual and useful.
The expert oversees the Buying Guide only, and does not determine the products and services featured.
Every mybest article is crafted with hours of in-depth research and interviews with experts. Each month, we are continually expanding our database of products based on our research. By emphasizing user insight and reliable information, we deliver trustworthy content to readers.
Dental abscesses or infections – Pus buildup from untreated infections causes severe pain and swelling.
Cracked or damaged teeth – Fractures can expose nerves, leading to discomfort.
Loose or broken fillings – A damaged filling can expose the sensitive inner tooth.
Impacted teeth – Particularly wisdom teeth that partially erupt without enough space.
Braces issues – Discomfort caused by orthodontic adjustments.
Gum disease – Inflammation and infection affecting the gums and tooth stability.
Teeth grinding (bruxism) – Excessive grinding that wears down enamel and causes pain.
Tooth sensitivity – Pain triggered by hot, cold, or sweet foods.

Prevention is better than cure. Routine dental examination every 6 months is recommended.
Pregnant and breastfeeding women should be cautious when taking pain relievers. Paracetamol is the safest option for pain relief, while Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and mefenamic acid should be avoided, especially after 20 weeks of pregnancy, due to potential risks to the baby.
Since medicine labels may not always indicate pregnancy safety, it’s best to consult a doctor before taking any medication to ensure both maternal and infant health.

20 weeks onwards, it may cause rare and serious kidney problems in the unborn baby. Fetal renal dysfunction and neonatal complications are most likely to occur.
Down with a bad toothache? Finding the right over-the-counter medicine can be a lifesaver, but with so many choices, it's hard to know what actually works. Before you grab just anything, here's a quick guide to help you choose the best medicine for your toothache.
Toothaches can range from mild discomfort to severe, persistent pain. Choosing the right medicine depends on the severity of symptoms and the cause of the pain. For minor toothaches, over-the-counter (OTC) pain relievers can help, while more severe cases may require stronger medications or professional intervention.
Paracetamol – A safe and effective choice for pain relief; however, daily intake should not exceed 4000mg to prevent liver damage.
Ibuprofen – Reduces both pain and inflammation; best taken with food to avoid stomach irritation, especially in high doses.
Mefenamic Acid – Another NSAID that helps relieve pain and swelling; should be taken with meals to minimize stomach discomfort.
These medications are easily accessible in tablet or capsule form and can provide quick relief for minor toothaches. Always follow the recommended dosage to ensure safe and effective use.
For intense or prolonged tooth pain, higher-dose NSAIDs can provide stronger relief. These are particularly effective for severe pain caused by deep cavities, impacted wisdom teeth, or gum swelling.
Ibuprofen (400mg) – Helps manage severe pain and inflammation. The standard dosage for OTC ibuprofen is 200mg every 4–6 hours, with a maximum daily dose of 1200mg. Prescription-strength doses of 600mg or 800mg are available but should only be taken under medical supervision due to potential side effects.
Mefenamic Acid (500mg) – Provides strong pain relief and reduces swelling; should be taken with food to minimize stomach irritation.
While these medications can help control pain, they are not a permanent solution. If pain persists despite medication or is accompanied by fever, swelling, or pus, it may indicate an infection requiring antibiotics or professional treatment. Consulting a dentist is crucial to prevent further complications.

Higher doses are generally effective, but depending on the person's age, an overdose may occur. The proper dosage requires a dentist's prescription. For pregnant women or those who are expecting, it's best to consult an OBGYN before taking any pain reliever.
For those who prefer non-oral options, topical pain relievers like benzocaine gels and oral pain relief sprays can provide temporary relief by numbing the affected area. These products work directly on the gums or tooth, making them ideal for targeting specific pain points, such as cavities or erupting wisdom teeth.
However, their effects wear off quickly, so they are best used alongside oral pain relievers for sustained relief. Overuse of numbing gels can cause irritation, so following the recommended application is important. If the pain is severe or persistent, a dentist should still be consulted for proper diagnosis and treatment.
Always check if a medication is FDA-approved to ensure it has been tested for safety and effectiveness. You can verify its registration on the Philippine FDA website to avoid unregistered medicines, which may contain harmful or ineffective ingredients.
To ensure authenticity, buy only from licensed pharmacies, official brand stores, or reputable sellers on platforms like Lazada, Shopee, Watsons, and Mercury Drug. Check packaging, expiration dates, and proper labels to avoid counterfeit products. When in doubt, consult a pharmacist or purchase from a physical pharmacy for a safer and more reliable option.
Products | Image | Click to purchase | Key features | Details | |||||
|---|---|---|---|---|---|---|---|---|---|
Key Ingredients | Best For | FDA-Approved | Content | Dosage | |||||
1 | Unilab Biogesic | ![]() | Fast-Acting Paracetamol Tablets for Common Aches | Paracetamol | Mild to Moderate Pain | 10 Tablets | 500 mg | ||
2 | Bayer Saridon | ![]() | Triple-Action Tablets for Fever and Pain Relief in Just 5 Minutes | Paracetamol, Propyphenazone, Caffeine | Mild to Moderate Pain | 10 Tablets | 250 mg / 150 mg / 50 mg | ||
3 | Unilab Rexidol Forte | ![]() | Get Fast Relief With a Paracetamol and Caffeine Combo | Paracetamol | Mild to Moderate Pain | 100 Tablets | 500 mg / 65 mg | ||
4 | TGP Toothache Drops Oral | ![]() | Clove Oil-Infused Toothache Drops With a Soothing Effect | Eugenol | Mild to Moderate Pain | 7.5 mL | 1.25mg | ||
5 | Unilab Medicol Advance | ![]() | Starts Working in 5 Minutes To Relieve Pain | Ibuprofen | Severe or Persistent Tooth Pain | 10 Softgels | 400mg | ||
6 | Dann's Toothache Drops | ![]() | Fast-Acting Relief for Sudden Dental Pain | Eugenol | Mild to Moderate Pain | 7.5mL | 1.25mg | ||
7 | Pfizer Advil Liqui-gel | ![]() | Reliable Pain Relief for Headaches, Fever, and Body Aches | Ibuprofen | Severe or Persistent Tooth Pain | 10 Softgels | 400mg | ||
8 | J. Chemie Eugenol Toothache Drops | ![]() | Soothes Toothache Pain Rapidly With Eugenol | Eugenol | Severe or Persistent Tooth Pain | 7.5mL | 1.25mg | ||
9 | Southstar Drug Mefenamic Acid | ![]() | Budget-Friendly Pain Relief for Everyday Aches | Mefenamic Acid | Mild to Moderate Pain | 1 Tablet | 500 mg | ||
10 | Unilab Dolfenal | ![]() | Targets Pain at Its Source With Mefenamic Acid | Mefenamic Acid | Severe or Persistent Tooth Pain | 1 Tablet | 250 mg | ||
| Key Ingredients | Paracetamol |
|---|---|
| Dosage | 500 mg |
Features and benefits:
Reviews mention:
Users appreciate its fast, reliable relief for headaches and fever, though some still find the tablet slightly large. Pregnant and breastfeeding women also like having a safe, effective option. Overall, many rely on it as their go-to for quick recovery from fever and common aches.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Tablets |
| Key Ingredients | Paracetamol, Propyphenazone, Caffeine |
|---|---|
| Dosage | 250 mg / 150 mg / 50 mg |
Features and benefits:
Reviews mention:
Buyers who suffer from migraines frequently mention the swift and lasting relief this triple-action formula provides. It is a preferred choice for severe headaches, with many opting for it over other brands. Its reliable effectiveness keeps them coming back.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Tablets |
| Key Ingredients | Paracetamol |
|---|---|
| Dosage | 500 mg / 65 mg |
Features and benefits:
Reviews mention:
Users find this combination effective for tension headaches and migraines and note that it also helps improve alertness. A few mention that clearer caffeine warnings would benefit caffeine-sensitive individuals. Overall, buyers like its fast and reliable relief.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 100 Tablets |
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
Features and benefits:
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5 mL |
| Key Ingredients | Ibuprofen |
|---|---|
| Dosage | 400mg |
Features and benefits:
Reviews mention:
Customers share that this tablet works quickly for headaches, stomach discomfort, and migraines. Many also note that it’s effective for period pain and reliable to keep on hand for sudden flare-ups. Users appreciate how easily it can be taken, making it a go-to option when pain hits.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Softgels |
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5mL |
| Key Ingredients | Ibuprofen |
|---|---|
| Dosage | 400mg |
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 10 Softgels |
| Key Ingredients | Eugenol |
|---|---|
| Dosage | 1.25mg |
Buyers report fast numbing for severe toothaches, often using it overnight until dentist appointments. Many highlight its clove-like scent as familiar and comforting from traditional remedies. Users caution about brief stinging on open wounds and stress seeing a dentist promptly.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 7.5mL |
| Key Ingredients | Mefenamic Acid |
|---|---|
| Dosage | 500 mg |
Features and benefits:
Reviews mention:
A lot of users consider this a trusted medication because it's so reliable when they need fast relief. People say it's especially great for tackling stubborn headaches and getting rid of menstrual cramps quickly. Plus, reviewers appreciate that the tablets are easy to swallow and that the delivery options make getting them very convenient.
| Best For | Mild to Moderate Pain |
|---|---|
| FDA-Approved | |
| Content | 1 Tablet |
| Key Ingredients | Mefenamic Acid |
|---|---|
| Dosage | 250 mg |
Features and benefits:
Reviews mention:
Reviewers often turn to this tablet for severe aches, including intense headaches and dental pain. Many trust its effectiveness and the reliability of a trusted company like Unilab. They frequently choose it when they need strong, dependable relief.
| Best For | Severe or Persistent Tooth Pain |
|---|---|
| FDA-Approved | |
| Content | 1 Tablet |
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Our buying guide was carefully researched and crafted by the mybest team of writers and editors, in collaboration with the expert featured in this article. We used the buying guide as a basis for choosing and ranking the product recommendations, and we looked at reviews and ratings from different E-commerce sites like Lazada, Shopee, and more.
No. 1: Unilab|Biogesic
No. 2: Bayer|Saridon
No. 3: Unilab|Rexidol Forte
No. 4: TGP|Toothache Drops Oral
No. 5: Unilab|Medicol Advance
View Full RankingThe descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.




























