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Japanese eye dropsHelping You Find the Best
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Japanese eye dropsHelping You Find the Best
  • 10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More 1
  • 10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More 2
  • 10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More 3
  • 10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More 4
  • 10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More 5

10 Best Japanese Eye Drops in the Philippines 2025 | Rohto, Santen, and More

Japanese eye drops are a quick, effective solution for tired, irritated eyes, uniquely combining advanced technology with traditional Japanese remedies. Known for their potent ingredients and refreshing formulas, these eye drops focus on providing fast relief from redness, dryness, and discomfort, especially for frequent screen users.


In this guide, you’ll find a helpful selection of Japanese eye drops that are available over the counter and easy to purchase on Shopee and Lazada. We’ve curated top picks tailored to different eye care needs, making it simple to find the ideal drops for your specific concerns.

Last updated 03/17/2025

Quick List - Top Japanese Eye Drops

1

Rohto

Cool Eye Drops
Cool Eye Drops

Cooling Eye Drops for Comfortable, Refreshed Eyes

2

Rohto

Vita 40 Alpha Eye Drops
Vita 40 Alpha Eye Drops

Revitalize Dry, Fatigued Eyes With Vitamins B6 and E

3

Santen

Sancoba Tired Eyes Relief
Sancoba Tired Eyes Relief

Refresh and Energize Your Eyes With Vitamin B12

4

Rohto

Aqua Eye Drops
Aqua Eye Drops

Provides Long-Lasting Hydration To Both Wearers and Non-Wearers of Contact Lens

5

Rohto

Z! Eye Drops
Z! Eye Drops

Cooling Eye Drops That Revitalizes Tired Eyes

Kyra Bernadette Yao
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Kyra Bernadette Yao

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Table of Contents

What Are the Distinct Features of Japanese Eye Drops?

What Are the Distinct Features of Japanese Eye Drops?

Japanese eye drops stand out for their advanced formulas, designed to tackle issues like digital eye strain, dryness, and age-related fatigue. They offer options for quick relief or lasting hydration, with features like thick solutions for extended moisture and cooling effects to soothe tired eyes. Key ingredients—like taurine for cell repair, sodium chondroitin sulfate for moisture, and protective vitamins and herbal extracts—help shield against environmental stressors like blue light.

How to Choose a Japanese Eye Drops – Buying Guide

Choosing the right Japanese eye drops can be challenging, especially if you’re unfamiliar with them. Our guide simplifies the options by focusing on your specific eye condition and the key factors to consider.

1

Choose a Formulation Based on Your Specific Needs

Start by choosing a formulation tailored to your specific eye needs. Whether you’re dealing with dryness, allergies, redness, or general eye fatigue, each type of eye drop offers unique ingredients to provide targeted relief. Read on to learn more.

For Dry Eyes: Eye Drops with Lubricants Help to Soothe and Rehydrate

For Dry Eyes: Eye Drops with Lubricants Help to Soothe and Rehydrate

Ingredients like glycerin and carboxymethylcellulose act as moisturizers, rehydrating the eye's surface and soothing any discomfort from dryness. These lubricating drops are ideal for those who spend long hours in front of screens or in air-conditioned environments, where moisture loss is common.


In addition to providing moisture, some may also include ingredients that protect against environmental irritants, such as dust or pollen, which can worsen dryness. Look for gentle, non-stinging formulas that can be used multiple times a day, especially if you have sensitive eyes.

For Allergies: Eye Drops with Antihistamines Relieve Irritation

For Allergies: Eye Drops with Antihistamines Relieve Irritation

For allergies, eye drops with antihistamines are a great choice to relieve itching, redness, and irritation caused by allergens. These eye drops are especially helpful during allergy season or if you’re frequently exposed to pollen, pet dander, or dust. These allergy-relief eye drops are designed for fast action and are gentle enough for regular use, making them a convenient solution for allergy sufferers.

For Redness and Puffiness: Eye Drops with Decongestants Offer Fast Relief

For Redness and Puffiness: Eye Drops with Decongestants Offer Fast Relief
Decongestants like phenylephrine work by narrowing blood vessels in the eyes, which reduces redness and gives eyes a refreshed and brighter look. These eye drops are ideal for those who experience temporary redness from lack of sleep, allergies, or irritants.


If you’re prone to eye puffiness, some of these formulas also include ingredients that soothe and cool, giving tired eyes a revitalizing boost. However, decongestant drops should be used sparingly; daily use isn’t recommended as they can cause rebound redness, a condition where redness worsens after the drops wear off.

For Eye Fatigue: Eye Drops with Vitamin B12 and A Refresh Tired Eyes

For Eye Fatigue: Eye Drops with Vitamin B12 and A Refresh Tired Eyes

These vitamins help nourish and protect your eyes, easing strain and tiredness from extended screen time or harsh lighting. Vitamin B12 supports eye health by reducing oxidative stress, which can alleviate fatigue. 


Similarly, vitamin A maintains a smooth, hydrated eye surface, reducing dryness and irritation while strengthening natural defenses. Together, they keep your eyes feeling comfortable and refreshed throughout the day.

2

Go for Gentle, Non-irritating Formulas to Ensure Comfort for Sensitive Eyes

Go for Gentle, Non-irritating Formulas to Ensure Comfort for Sensitive Eyes

If you have sensitive eyes, a non-irritating formula can ensure comfort without stinging or redness. Eye drops for sensitive eyes often use mild, soothing ingredients, avoiding harsh chemicals or strong preservatives.


These gentle formulas are also ideal for daily use, relieving dryness and discomfort without overwhelming your eyes. Some even include moisturizers or calming ingredients, like hyaluronic acid or chamomile extract, to hydrate and soothe delicate eye tissue.

3

Consider Eye Drops With Menthol if You Want a Refreshing, Cooling Sensation

Consider Eye Drops With Menthol if You Want a Refreshing, Cooling Sensation

Menthol works by gently stimulating the eye’s surface, providing a soothing effect that helps relieve heaviness or eye strain, especially after long hours of work or screen time. This cooling effect can make eye drops with menthol ideal for people dealing with eye fatigue, especially in warm climates or busy environments where eyes can feel extra tired. However, the intensity of the cooling sensation can vary, so if you have sensitive eyes, look for milder formulations.

4

Be Mindful of Expiration Dates to Ensure Freshness and Safety

Be Mindful of Expiration Dates to Ensure Freshness and Safety

Expired eye drops may lose effectiveness and could even lead to irritation or infection if the ingredients break down over time. Before purchasing, always look for the expiration date printed on the packaging, and avoid using any product that’s past its date.


Once opened, eye drops have a limited shelf life—often about three months. To keep them effective and safe, store your eye drops in a cool, dry place, and avoid touching the dropper tip to prevent contamination.

Was the Buying Guide helpful?

10 Best Japanese Eye Drops to Buy Online

The products we introduce below were carefully curated by the mybest team, from the best-sellers of E-commerce sites like Lazada, and using the points mentioned in our detailed and thoroughly researched buying guide.
Popularity
Filter
Products
Image
Click to purchase
Key features
Details
Formulation Type
Notable Ingredients
With Menthol
Recommended Dosage
Special Precaution
Net Weight
1

Rohto

Cool Eye Drops

Rohto  Cool Eye Drops 1

Cooling Eye Drops for Comfortable, Refreshed Eyes

Cooling、Lubricating

None

1-2 drops per eye, can be used 5-6 times per day

Suitable for use with or without contact lenses

13ml

2

Rohto

Vita 40 Alpha Eye Drops

Rohto Vita 40 Alpha Eye Drops 1

Revitalize Dry, Fatigued Eyes With Vitamins B6 and E

Redness-Relieving、Itch-Relieving、Lubricating

Vitamin B6、Vitamin E

1-3 drops per use and up to 5 times per day

Not Specified

12ml

3

Santen

Sancoba Tired Eyes Relief

Santen Sancoba Tired Eyes Relief 1

Refresh and Energize Your Eyes With Vitamin B12

Lubricating

Cyanocobalamin (Vitamin B12)、Boric Acid、Sodium Borate

Apply 1-2 drops at a time to the eye, 3 to 5 times daily

Not Specified

5ml

4

Rohto

Aqua Eye Drops

Rohto  Aqua Eye Drops 1

Provides Long-Lasting Hydration To Both Wearers and Non-Wearers of Contact Lens

Lubricating

None

1-2 drops per eye, can be used 5 to 6 times per day.

Suitable for use with or without contact lenses

13ml

5

Rohto

Z! Eye Drops

Rohto  Z! Eye Drops 1

Cooling Eye Drops That Revitalizes Tired Eyes

Cooling、Lubricating

Vitamin B6

2-3 drops at a time, 5 to 6 times daily

Not Specified

12ml

6

Lion Smile

40 EX Vitamin Eye Drops

Lion Smile  40 EX Vitamin Eye Drops 1

Has Vitamins A, E, and B6 to Nourish Strained Eyes

Lubricating、Redness-Relieving、Itch-Relieving

Vitamin E、Vitamin A、Vitamin B6

1-2 drops in each eye, maximum of 6 doses each day.

Contains No Preservatives

12ml

7

Rohto

Lycée Contact Lens Rewetting Eye Drops

Rohto Lycée Contact Lens Rewetting Eye Drops 1

Helps Prolong Comfort for Contact Lens Wearers

Lubricating

Hypromellose、Sodium Chondroitin Sulfate、Sodium Hyaluronate

1-3 drops at a time for each eye, up to 6 times a day

Can be used with soft, hard, O2, disposable, and color contact lens

8ml

8

Santen

FX Neo V Plus Eye Drops

Santen FX Neo V Plus Eye Drops 1

Enriched With Taurine and Vitamin B6 To Invigorate Bleary Eyes

Lubricating、Redness-Relieving

Vitamin B6、Taurine

2-3 drops per use and up to 6 times per day

Not Specified

12ml

9

Santen

Sante Beautéye Eye Drops

Santen Sante Beautéye Eye Drops 1

Brightens The Whites Of Your Eyes With This Moisturizing and Redness-Relieving Eye Drops

Lubricating、Redness-Relieving

Cyanocobalamin (Vitamin B12)、Sodium Chondroitin Sulfate、Taurine

1-2 drops per use, 5 to 6 times a day

Excessive use may cause abnormal glare or even redness, For use on children, use under parental guidance and supervision, Do not allow the tip of the container to come into contact with the eyes, eyelids or eyelashes (the chemical solution may become contaminated or cloudy due to contamination of the eyes, eyelids and other bacteria).

12ml

10

Taisho

Iris CL-I Neo Artificial Tears

Taisho Iris CL-I Neo Artificial Tears 1

Preservative-Free Disposable Eye Drops Ideal For Contact Lens Users

Lubricating

Sodium Chloride、Potassium Chloride

2-3 drops each time, use 3 to 6 times daily

Box of 30 Disposable Pieces. No Preservatives. Use immediately after opening, do not keep the remaining liquid for use, it should be discarded in time.

0.4ml

If you don't see the product you're looking for, you can request that it be listed.
No.1

Rohto
Cool Eye Drops

Cool Eye Drops 1
Source:watsons.com.ph
Reference price
₱175
Low Mid
Reference price
₱175
Low Mid

Cooling Eye Drops for Comfortable, Refreshed Eyes

Features and benefits:
  • Provides instant level 5 cooling relief with menthol
  • Moisturizes and soothes dry, irritated eyes with sodium hyaluronate and hypromellose
  • Soothes strained, tired eyes from minor irritations caused by contact lenses, digital eye strain, wind, or dust
  • Safe for use with all contact lenses and contains no medicinal active ingredients

Reviews mention:
Users say it provides instant relief for tired, dry eyes, making it a must-have for long workdays or commutes. They like the cooling effect that helps wake up sleepy eyes, and many find it easy to use and convenient for busy days.
Formulation TypeCooling、Lubricating
Notable IngredientsNone
With Menthol
Recommended Dosage1-2 drops per eye, can be used 5-6 times per day
Special PrecautionSuitable for use with or without contact lenses
Net Weight13ml
View all
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No.2

Rohto
Vita 40 Alpha Eye Drops

Reference price
₱170
Low Mid

Revitalize Dry, Fatigued Eyes With Vitamins B6 and E

Features and benefits:
  • Contains vitamin B6 and vitamin E to help reduce eye fatigue, irritation, and redness
  • Relieves discomfort and prevents infection from exposure to dust, chlorine, and UV rays
  • Reduces swelling and "blurred" sclera for brighter, lighter eyes
  • Helps reduce eye strain and supports eye health with potassium and sodium

Reviews mention:
Buyers share that it delivers instant comfort for dry, irritated eyes, with many calling it a lifesaver after long hours of screen time. They also appreciate the fast-acting relief without any stinging or discomfort.
Formulation TypeRedness-Relieving、Itch-Relieving、Lubricating
Notable IngredientsVitamin B6、Vitamin E
With Menthol
Recommended Dosage1-3 drops per use and up to 5 times per day
Special PrecautionNot Specified
Net Weight12ml
View all
No.3

Santen
Sancoba Tired Eyes Relief

Reference price
₱199
Low Mid

Refresh and Energize Your Eyes With Vitamin B12

Features and benefits:
  • Contains vitamin B12 to help energize and refresh tired, strained eyes
  • Ideal for those who work long hours on screens or experience frequent eye fatigue
  • Suitable for users aged 10 and above
  • Made by Santen Pharmaceutical Co. Ltd, a trusted Japanese company

Reviews mention:
Reviewers find it more effective than other eye drops for relieving computer-related eye strain. Some also share that it was recommended by their eye doctor and provides noticeable comfort.
Formulation TypeLubricating
Notable IngredientsCyanocobalamin (Vitamin B12)、Boric Acid、Sodium Borate
With Menthol
Recommended DosageApply 1-2 drops at a time to the eye, 3 to 5 times daily
Special PrecautionNot Specified
Net Weight5ml
View all
No.4

Rohto
Aqua Eye Drops

Reference price
₱184
Low Mid

Provides Long-Lasting Hydration To Both Wearers and Non-Wearers of Contact Lens

Persistent dry eyes can be irritating, but Rohto Aqua Eye Drops could be the solution for you! This advanced formula contains hyaluronic acid, a powerful moisture-retaining ingredient that keeps your eyes feeling comfortably hydrated throughout the day while reducing dryness.

Individuals suffering from chronic dry eyes, contact lens wearers experiencing dryness, and those suffering from dry eyes caused by environmental factors such as air conditioning and pollution could benefit from this lubricating eye solution.
Formulation TypeLubricating
Notable IngredientsNone
With Menthol
Recommended Dosage1-2 drops per eye, can be used 5 to 6 times per day.
Special PrecautionSuitable for use with or without contact lenses
Net Weight13ml
View all
No.5

Rohto
Z! Eye Drops

Reference price
₱280
Mid

Cooling Eye Drops That Revitalizes Tired Eyes

Exhausted after a sleepless night or need a pick-me-up for tired eyes? Use a few drops of the Rohto Z! Eye Drops to refresh them. This cooling solution provides fast-acting redness relief by brightening tired eyes, while soothing and revitalizing irritated eyes.

It has a special free angle nozzle so you can apply the drops at any angle! Customers rave about how it effectively reduces redness and leaves eye feeling super cool, especially after a tiring night.
Formulation TypeCooling、Lubricating
Notable IngredientsVitamin B6
With Menthol
Recommended Dosage2-3 drops at a time, 5 to 6 times daily
Special PrecautionNot Specified
Net Weight12ml
View all
No.6

Lion Smile
40 EX Vitamin Eye Drops

40 EX Vitamin Eye Drops 1
Source:jagodo.net
Reference price
₱209
Low Mid

Has Vitamins A, E, and B6 to Nourish Strained Eyes

Excess computer work, reading or driving could result to eye fatigue. Aside from scheduling regular breaks for your eyes, adding moisture to them can help to prevent the feeling of dryness. Lion Smile 40 EX Vitamin Eye Drops nourishes your eyes with its vitamin-enriched formula.

This contains vitamins A, E, and B6 to alleviate tired, strained eyes while supporting overall eye health and comfort. Vitamin A in particular helps in the production of certain pigments in the retina for your eyes to work properly, plus ensures that the eyes are properly lubricated!
Formulation TypeLubricating、Redness-Relieving、Itch-Relieving
Notable IngredientsVitamin E、Vitamin A、Vitamin B6
With Menthol
Recommended Dosage1-2 drops in each eye, maximum of 6 doses each day.
Special PrecautionContains No Preservatives
Net Weight12ml
View all
No.7

Rohto
Lycée Contact Lens Rewetting Eye Drops

Lycée Contact Lens Rewetting Eye Drops 1
Source:jp.rohto.com
Reference price
₱348.61
High Mid
Reference price
₱348.61
High Mid

Helps Prolong Comfort for Contact Lens Wearers

Prolonged wear of contact lenses may make your eyes feel dry and uncomfortable, leaving your eyes in need of quick, soothing relief. Rohto's Lycée Contact Lens Drops are made specifically for contact lens wearers. These lubricating drops not only relieve dryness but also refresh tired eyes, allowing you to continue wearing your lenses comfortably throughout the day.

Whether you use hard, soft, O2, or disposable lenses, Lycée Contact Lens Drops are an essential addition to your eye care routine. With a bottle on hand, you’ll have a convenient solution to address eye strain and dryness whenever you need it, ensuring all-day comfort and clarity for your eyes.
Formulation TypeLubricating
Notable IngredientsHypromellose、Sodium Chondroitin Sulfate、Sodium Hyaluronate
With Menthol
Recommended Dosage1-3 drops at a time for each eye, up to 6 times a day
Special PrecautionCan be used with soft, hard, O2, disposable, and color contact lens
Net Weight8ml
View all
No.8

Santen
FX Neo V Plus Eye Drops

FX Neo V Plus Eye Drops 1
Source:santen.com
Reference price
₱420
High Mid

Enriched With Taurine and Vitamin B6 To Invigorate Bleary Eyes

Getting blurry vision and red eyes from the long screen time? Give your eyes a break with Santen FX Neo V Plus Eye Drops! It's packed with Taurine to boost eye tissue metabolism to combat fatigue, and Vitamin B6 to help with clearer vision.

Say goodbye to discomfort after computer work or long drives and reduce eye irritation with just a few drops per eye. Workers who need to work in front of the computer all day and people experiencing occasional redness may benefit from this eye drop solution.
Formulation TypeLubricating、Redness-Relieving
Notable IngredientsVitamin B6、Taurine
With Menthol
Recommended Dosage2-3 drops per use and up to 6 times per day
Special PrecautionNot Specified
Net Weight12ml
View all
No.9

Santen
Sante Beautéye Eye Drops

Reference price
₱858
High

Brightens The Whites Of Your Eyes With This Moisturizing and Redness-Relieving Eye Drops

Struggling with red eyes can make one look sick or tired. With Santen Sante Beauteye Eye Drops, you can say goodbye to tired, achy eyes! This formula combines Vitamin B12 to tackle tiredness and muscle strain, Tetrahydrozoline hydrochloride to brighten the whites of your eyes, and Chondroitin sulfate sodium to protect and hydrate your corneas.

With its rose-scented formula and elegant packaging, Santen Sante Beauteye is the perfect addition to your beauty routine!
Formulation TypeLubricating、Redness-Relieving
Notable IngredientsCyanocobalamin (Vitamin B12)、Sodium Chondroitin Sulfate、Taurine
With Menthol
Recommended Dosage1-2 drops per use, 5 to 6 times a day
Special PrecautionExcessive use may cause abnormal glare or even redness, For use on children, use under parental guidance and supervision, Do not allow the tip of the container to come into contact with the eyes, eyelids or eyelashes (the chemical solution may become contaminated or cloudy due to contamination of the eyes, eyelids and other bacteria).
Net Weight12ml
View all
No.10

Taisho
Iris CL-I Neo Artificial Tears

Reference price
₱610
High Mid

Preservative-Free Disposable Eye Drops Ideal For Contact Lens Users

Do your contact lenses leave your eyes feeling dry and irritated? Taisho Iris CL-I Neo Artificial Tears offer soothing relief without compromising your lenses. This preservative-free formula provides long-lasting moisture and keeps eyes hydrated. It also soothes irritation associated with dry contact lens wear.

Frequent wearers of contac lenses who experience dryness or irritation, or those using soft, hard, disposable, or O2 contact lenses can benefit from this formula. With 30 pieces per box, Taisho Iris CL-I Neo is easy to carry and use anytime for quick relief!
Formulation TypeLubricating
Notable IngredientsSodium Chloride、Potassium Chloride
With Menthol
Recommended Dosage2-3 drops each time, use 3 to 6 times daily
Special PrecautionBox of 30 Disposable Pieces. No Preservatives. Use immediately after opening, do not keep the remaining liquid for use, it should be discarded in time.
Net Weight0.4ml
View all

Frequently Asked Questions

Below are some of the most asked questions on the web answered by the mybest team.

Are Japanese Eye Drops Safe for Daily Use?

Yes, many Japanese eye drops are safe for daily use, particularly those designed for regular issues like dryness, tiredness, or mild irritation. However, avoid using decongestant drops (for redness) daily. Always check the instructions on the label to confirm safe usage frequency and choose a gentle formula if you have sensitive eyes.

Can I Use Japanese Eye Drops With Contact Lenses?

Some Japanese eye drops are formulated to be contact lens-friendly, but it’s important to verify this on the packaging. Look for eye drops labeled "safe for contact lenses" or "contact-friendly" to prevent potential irritation or damage to your lenses. If uncertain, remove your lenses before applying eye drops and wait a few minutes before reinserting them.

How Should I Store Japanese Eye Drops, and How Long Do They Last After Opening?

Japanese eye drops should be stored in a cool, dry place, away from direct sunlight to maintain effectiveness. Once opened, most eye drops are best used within 1–3 months to avoid contamination. Check the product’s instructions, as some may have specific storage guidelines or shorter shelf lives.

How We Chose and Ranked Our Product Recommendations

Our buying guide was carefully researched and crafted by the mybest team of writers and editors. We used the buying guide as a basis for choosing and ranking the product recommendations, and we looked at reviews and ratings from different E-commerce sites like Lazada, Shopee, and more.

Top 5 Japanese Eye Drops

No. 1: Rohto Cool Eye Drops

No. 2: RohtoVita 40 Alpha Eye Drops

No. 3: SantenSancoba Tired Eyes Relief

No. 4: Rohto Aqua Eye Drops

No. 5: Rohto Z! Eye Drops

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The descriptions of each product are referenced from content available on manufacturer, brand, and e-commerce sites.

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